{"id":944,"date":"2019-09-26T12:24:26","date_gmt":"2019-09-26T10:24:26","guid":{"rendered":"http:\/\/confolab.sav.sk\/ovsb\/en\/?page_id=944"},"modified":"2019-09-27T09:47:36","modified_gmt":"2019-09-27T07:47:36","slug":"gender-issues-in-the-cardiovascular-field","status":"publish","type":"page","link":"https:\/\/confolab.sav.sk\/ovsb\/en\/activities\/events\/gender-issues-in-the-cardiovascular-field\/","title":{"rendered":"Gender issues in the cardiovascular field"},"content":{"rendered":"<p><script type=\"text\/javascript\">\n<!--\nfunction launch(newURL, newName, newFeatures, orgName) {\n  var remote = open(newURL, newName, newFeatures);\n  if (remote.opener == null)\n    remote.opener = window;\n  remote.opener.name = orgName;\n  return remote;\n}\n\nfunction launchRemote(name) {\n  var address =  name;\n  myRemote = launch(address ,\n                    \"Okno\",\n                    \"height=500, width=850, left=50, top=50, alwaysLowered=0, alwaysRaised=0, channelmode=0, dependent=0, directories=0, fullscreen=0, hotkeys=1, location=0, menubar=0, resizable=0, scrollbars=0, status=0, titlebar=1, toolbar=0, z-lock=0\",\n                    \"myWindow\");\n}\n\/\/ -->>\n<\/script><button onclick=\"goBack()\">Back<\/button><br \/>\n<script>\t \t \nfunction goBack() { window.history.go(-1); }\t \t \n<\/script><\/p>\n<h2>Prof. Ren\u00e9e Ventura-Clapier<br \/>\nEmeritus Research Director<br \/>\nCentre National de la Recherche Scientifique France <\/h2>\n<p>U-1180 Inserm Signaling and Cardiovascular pathophysiology, Universit\u00e9 Paris-Sud, Ch\u00e2tenay-Malabry, France<\/p>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"2\">\n<tbody>\n<tr>\n<td>Biomedical Research Centre seminar<br \/>\nWednesday 18 September 2019 at 1 pm<br \/>\nThe large conference room of the Institute of Virology<\/p>\n<p><b>Lecture abstract<\/b><\/p>\n<p>It is increasingly acknowledged that a sex and gender specificity affects the occurrence, development, and consequences of cardiovascular diseases (CVD). The rate of CVD is lower in non- menopausal women than in men of the same age, but this rate increases with age and becomes the major cause of female mortality. These gender differences include biological but also socio-cultural parameters. They affect symptomatology, epidemiology, physiopathology, medical approach, effectiveness of the treatments, side effects, prognosis and prevention of CVD. Biological differences arise from sex chromosomes, hormones and epigenetic factors. Sexual hormone receptors are present in the different cell populations of the cardiovascular system rendering them sensitive to circulating hormones. Among the numerous cell processes present with a sexual dimorphism, energy metabolism is of special interest. Various sex differences has been noted in mitochondria that affect biogenesis, specific activities, calcium handling and oxidative stress for example. Paradoxically, the Male\/Female representation in clinical and experimental studies shows a very clear disproportion to the disadvantage of women. This introduces a bias in translational research, and in clinical concepts and the development of CV therapies that are less effective and have more side effects in women. <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"H3\">Snapshots:<\/span><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" title=\"\" src=\"http:\/\/confolab.sav.sk\/ovsb\/wp-content\/uploads\/Renee-Ventura-Clapier.png\" alt=\"\" width=\"245\" height=\"245\" hspace=\"3\" vspace=\"3\" \/> <img decoding=\"async\" loading=\"lazy\" title=\"\" src=\"http:\/\/confolab.sav.sk\/ovsb\/wp-content\/uploads\/Renee-a-spol.jpg\" alt=\"\" width=\"340\" height=\"245\" hspace=\"3\" vspace=\"3\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Back Prof. Ren\u00e9e Ventura-Clapier Emeritus Research Director Centre National de la Recherche Scientifique France U-1180 Inserm Signaling and Cardiovascular pathophysiology, Universit\u00e9 Paris-Sud, Ch\u00e2tenay-Malabry, France Biomedical&#8230;<span class=\"excerpt_more\"><a href=\"https:\/\/confolab.sav.sk\/ovsb\/en\/activities\/events\/gender-issues-in-the-cardiovascular-field\/\">\u010d\u00edta\u0165 \u010falej &raquo;<\/a><\/span><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":122,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/confolab.sav.sk\/ovsb\/en\/wp-json\/wp\/v2\/pages\/944"}],"collection":[{"href":"https:\/\/confolab.sav.sk\/ovsb\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/confolab.sav.sk\/ovsb\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/confolab.sav.sk\/ovsb\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/confolab.sav.sk\/ovsb\/en\/wp-json\/wp\/v2\/comments?post=944"}],"version-history":[{"count":5,"href":"https:\/\/confolab.sav.sk\/ovsb\/en\/wp-json\/wp\/v2\/pages\/944\/revisions"}],"predecessor-version":[{"id":948,"href":"https:\/\/confolab.sav.sk\/ovsb\/en\/wp-json\/wp\/v2\/pages\/944\/revisions\/948"}],"up":[{"embeddable":true,"href":"https:\/\/confolab.sav.sk\/ovsb\/en\/wp-json\/wp\/v2\/pages\/122"}],"wp:attachment":[{"href":"https:\/\/confolab.sav.sk\/ovsb\/en\/wp-json\/wp\/v2\/media?parent=944"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}