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Baglaeva I, Iaparov B, Zahradnik I, Zahradnikova A (2023). Analysis of noisy transient signals based on Gaussian process regression. Biophys J 122: 451–459. doi: 10.1016/j.bpj.2023.01.003. |
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Iaparov B, Baglaeva I, Zahradnik I, Zahradnikova A (2022). Magnesium ions moderate calcium-induced calcium release in cardiac calcium release sites by binding to ryanodine receptor activation and inhibition sites. Front Physiol 12: 805956. doi: 10.3389/fphys.2021.805956. |
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Grimbert L, Sanz MN, Gressette M, Rucker-Martin C, Novotova M, Solgadi A, Karoui A, Gomez S, Bedouet K, Jacquet E, Lemaire C, Veksler V, Mericskay M, Ventura-Clapier R, Piquereau JM, Garnier A (2021): Spatiotemporal AMPK alpha 2 deletion in mice induces cardiac dysfunction, fibrosis and cardiolipin remodeling associated with mitochondrial dysfunction in males only. Biol Sex Differ, vol 12: 52. doi: 10.1186/s13293-021-00394-z. |
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Yin L, Zahradnikova A Jr, Rizzetto R, Boncompani S, Rabesahala de Meritens C, Zhang Y, Joanne P, Marques Sule E, Aguilar-Torres Y, Fernandez-Tenorio M, Villejoubert O, Li L, Wang YY, Mateo P, Nicolas V, Gerbaud P, Lai FA, Perrier R, Alvarez JL, Niggli E, Valdivia HH, Valdivia CR, Ramos-Franco J, Zorio E, Zissimopoulos S, Protasi F, Benitah JP, Gomez AM (2021): Impaired binding to junctophilin2 and nanostructural alteration in CPVT mutation. Circ Res 129: e35-e52 doi: 10.1161/CIRCRESAHA.121.319094. |
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Iaparov B, Zahradnik I, Moskvin AS, Zahradnikova A (2021): In silico simulations reveal that RYR distribution affects the dynamics of calcium release in cardiac myocytes. J Gen Physiol 153: e202012685 doi: 10.1085/jgp.202012685. |
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Novotova M, Zahradnikova A Jr, Nichtova Z, Kovac R, Kralova E, Stankovicova T, Zahradnikova A, Zahradnik I (2020): Structural variability of dyads relates to calcium release in rat ventricular myocytes. Sci Rep 10: 8076 doi: 10.1038/s41598-020-64840-5. |
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Pires Da Silva J, Monceaux K, Guilbert A, Gressette M, Piquereau J, Novotova M, Ventura-Clapier R, Garnier A, Lemaire C (2020): SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy. Cells. 9: E426 doi: 10.3390/cells9020426. |
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Iaparov B, Moskvin AS, Zahradnik I, Zahradnikova A (2019): Stochastic and deterministic approaches to modelling calcium release in cardiac myocytes at different spatial arrangements of ryanodine receptors. Eur Biophys J 48: 579–584 doi: 10.1007/s00249-019-01378-z. |
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Skrabanek P, Zahradnikova A Jr (2019): Automatic assessment of the cardiomyocyte development stages from confocal microscopy images using deep convolutional networks. PLoS One 14: e0216720, doi: 10.1371/journal.pone.0216720. |
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Cagalinec M, Zahradnikova A, Zahradnikova A Jr, Kovacova D, Paulis L, Kurekova S, Hotka M, Pavelkova J, Plaas M, Novotova M, Zahradnik I (2019). Calcium signaling and contractility in cardiac myocyte of wolframin deficient rats. Front Physiol 10: 172, doi: 10.3389/fphys.2019.00172. |
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Prola A, Nichtova Z, Pires Da Silva J, Piquereau J, Monceaux K, Guilbert A, Gressette M, Ventura-Clapier R, Garnier A, Zahradnik I, Novotova M, Lemaire C (2019): Endoplasmic reticulum stress induces cardiac dysfunction through architectural modifications and alteration of mitochondrial function in cardiomyocytes. Cardiovasc Res : doi: 10.1093/cvr/cvy197. |
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Hotka M, Zahradnik I (2017): Reconstruction of membrane current by deconvolution and its application to membrane capacitance measurements in cardiac myocytes. PLoS One 12: e0188452. |
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Mackova K, Zahradnikova A Jr, Hotka M, Hoffmannova B, Zahradnik I, Zahradnikova A (2017). Calcium release-dependent inactivation precedes formation of the tubular system in developing rat cardiac myocytes. Eur Biophys J 46: 691-703.
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Faltinova A, Tomaskova N, Antalik M, Sevcik J, Zahradnikova A (2017). The N-terminal region of the ryanodine receptor affects channel activation. Front Physiol 8: 443. |
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Petrovic P, Valent I, Cocherova E, Pavelkova J, Zahradnikova A (2015): Ryanodine receptor gating controls generation of diastolic calcium waves in cardiac myocytes. J Gen Physiol 145: 489-511. |
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Borko L, Bauerova-Hlinkova V, Hostinova E, Gasparik J, Beck K, Lai FA, Zahradnikova A, Sevcik J (2014): Structural insights into the human RyR2 N-terminal region involved in cardiac arrhythmias. Acta Cryst D70: 2897–2912. |
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Caffin F, Prola A, Piquereau J, Novotova M, David DJ, Garnier A, Fortin D, Alavi M, Veksler V, Ventura-Clapier R, Joubert F (2013): Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1-deficient mice. J Physiol 591: 6017-37. |
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Janicek R, Hotka M, Zahradnikova-Jr A, Zahradnikova A, Zahradnik I (2013): Quantitative analysis of calcium spikes in noisy fluorescent background. PLoS One 8: e64394. |
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Piquereau J, Caffin F, Novotova M, Lemaire C, Veksler V, Garnier A, Ventura-Clapier R, Joubert F (2013): Mitochondrial dynamics in the adult cardiomyocytes: which roles for a highly specialized cell? Front Physiol 4: 102. |
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Zahradnikova A, Zahradnik I (2012). Construction of calcium release sites in cardiac myocytes. Front Physiol 3: 322. |
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Nichtova Z, Novotova M, Kralova E, Stankovicova T (2012): Morphological and functional characteristics of models of experimental myocardial injury induced by isoproterenol. Gen Physiol Biophys 31: 141-51. |
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Janicek R, Zahradnikova-Jr A, Polakova E, Pavelkova J, Zahradnik I, Zahradnikova A (2012): Calcium spike variability in cardiac myocytes results from activation of small cohorts of RYR2 channels. J Physiol 590: 5091-5106. |
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Tencerova B, Zahradnikova A, Gaburjakova J, Gaburjakova M (2012): Luminal Ca2+ controls activation of the cardiac ryanodine receptor by ATP. J Gen Physiol 140: 93-108. |
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Piquereau J, Caffin F, Novotova M, Prola A, Garnier A, Mateo P, Fortin D, Huynh LH, Nicolas V, Alavi MV, Brenner C, Ventura-Clapier R, Veksler V, Joubert F (2012). Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload. Cardiovasc Res 94: 408-417. |
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Piquereau J, Novotova M, Fortin D, Garnier A, Ventura-Clapier R, Veksler V, Joubert F (2010). Postnatal development of mouse heart: formation of energetic microdomains. J Physiol.588: 2443-54. |
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Zahradnikova A, Valent I, Zahradnik I (2010): Frequency and release flux of calcium sparks in rat cardiac myocytes: a relation to RYR gating. J Gen Physiol 136: 101-116. |
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Parulek J, Sramek M, Cerveansky M, Novotova M, Zahradnik I (2009). A cell architecture modeling system based on quantitative ultrastructural characteristics. Methods Mol Biol. 500: 289-312. |
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Parulek J, Sramek M, Zahradnik I (2009). GeomCell Design of Cell Geometry. Recent Advances in the 3d Physiological Human, N. Magnenat-Thalmann et al. (eds.), Springer-Verlag London Ltd, p. 21-36. |
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Polakova E, Zahradnikova A Jr, Pavelkova J, Zahradnik I, Zahradnikova A (2008). Local calcium release activation by DHPR calcium channel openings in rat cardiac myocytes. J Physiol. 586: 3839-3854. |
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Joubert F, Wilding JR, Fortin D, Domergue-Dupont V, Novotova M, Ventura-Clapier R, Veksler V (2008). Local energetic regulation of sarcoplasmic and myosin ATPase is differently impaired in rats with heart failure. J Physiol. 586: 5181-5192. |
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Zahradnik I, Minarovic I, Zahradnikova A (2008). Inhibition of the cardiac L-type calcium channel current by antidepressant drugs. J Pharmacol Exp Ther. 324:977-984. |
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Zahradnikova A Jr, Polakova E, Zahradnik I, Zahradnikova A (2007). Kinetics of calcium spikes in rat cardiac myocytes. J Physiol 578: 677-691. |
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Novotova M, Pavlovicova M, Veksler VI, Ventura-Clapier R, Zahradnik I (2006). Ultrastructural remodeling of fast skeletal muscle fibers induced by invalidation of creatine kinase. Am J Physiol Cell Physiol. 291: C1279-1285. |
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Zahradnik I, Gyorke S, Zahradnikova A (2005). Calcium activation of ryanodine receptor channels–reconciling RyR gating models with tetrameric channel structure. J Gen Physiol. 126: 515-527. |
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Zahradnikova A, Kubalova Z, Pavelkova J, Gyorke S, Zahradnik I (2004). Activation of calcium release assessed by calcium release-induced inactivation of calcium current in rat cardiac myocytes. Am J Physiol Cell Physiol. 286: C330-41. |
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Zahradnikova A, Dura M, Gyorke I, Escobar AL, Zahradnik I, Gyorke S (2003). Regulation of dynamic behavior of cardiac ryanodine receptor by Mg2+ under simulated physiological conditions. Am J Physiol Cell Physiol. 285: C1059-1070. |
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Novotova M, Zahradnik I, Brochier G, Pavlovicova M, Bigard X, Ventura-Clapier R (2002). Joint participation of mitochondria and sarcoplasmic reticulum in the formation of tubular aggregates in gastrocnemius muscle of CK-/- mice. Eur J Cell Biol. 81: 101-106. |
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Kaasik A, Veksler V, Boehm E, Novotova M, Minajeva A, Ventura-Clapier R (2001). Energetic crosstalk between organelles: architectural integration of energy production and utilization. Circ Res. 89: 153-159. |
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Zahradnikova A, Zahradnik I, Gyorke I, Gyorke S (1999). Rapid activation of the cardiac ryanodine receptor by submillisecond calcium stimuli. J Gen Physiol. 114: 787-798. |
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Zahradnikova A, Zahradnik I (1996). A minimal gating model for the cardiac calcium release channel. Biophys J. 71: 2996-3012. |
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